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Breast Cancer
Breast cancer has the highest incidence rate among females. Among the patients with breast cancer, approximate 10% get breast cancer for the reason of heredity mutations which has 50% probability of being passed on to offspring and which other immediate relatives also have a high risk of carrying.
Case Story
The famous Hollywood star––Angelina Jolie published an article in the New York Times on May 14, 2013, revealing that she herself had undergone a preventive mastectomy.
Jolie's mother fought breast cancer for nearly a decade and died at the age of 56; her aunt died at the age of 61 of breast cancer; and her grandmother also died of cancer.
After gene detection, doctors discovered the mutation of Jolie's BRCA1 gene is present, which could sharply boost the Jolie's risk of developing breast and ovarian cancer. On doctors' suggestion, Jolie accepted the preventive mastectomy which steeply reduced her risk of developing cancer to 5%. And afterwards in 2015, Jolie accepted preventative laparoscopic bilateral salpingo-oophorectomy, reducing her risk of developing the hereditary ovarian cancer to the lowest level.
Scientific studies discovered that BRCA1 and BRCA2 gene are two important tumor suppressor genes which can repair the damaged DNA. That the mutation occurs in BRCA1/BRCA2 may very likely cause the mutation in other functional genes not to be repaired, lead to functional gene deficiency, and thus induce a series of cancers, among which the mainly two cancers are the hereditary breast cancer and ovarian cancer. The risk of developing breast cancer in BRCA1/BRCA2 mutation carriers will be largely elevated, with an earlier onset age of this cancer.

As showed in the figure, the probability of breast cancer in the people carrying the BRCA gene mutation is far higher than common people.
Burning Rock You Jian™
Lunched by Burning Rock Dx, Burning Rock You Jian™ hereditary breast gene detection can detect all at once more than 10 genes highly correlated with hereditary breast cancer including BRCA1/BRCA2, perform risk evaluation of hereditary breast cancer for females to reach the purpose of『early prevention, early intervention, early discovering and early treatment』, controlling risk for the future and protecting the life.

Applicable Populations

1. Breast cancer patients: This detection can confirm whether the cancer is the hereditary breast cancer, provide appropriate therapy, and also provide important reference information for the relatives.
2. People who have a high risk of disease: The people with high risk of hereditary breast cancer including the relatives of the patients with familial breast cancer are recommended to accept the detection.
3. Healthy people: All people who are concerned with breast health.

Service Procedure